Both western blotting and real-time PCR analysis showed that CAMSAP2 knockdown in MHCC97H cells significantly increased HDAC6 expression, and that HDAC6 was markedly downregulated in CAMSAP2-overexpressing Huh7 cells with no apparent change in the expression of αTAT1 in the transfected HCC cells (Figure 6G, Figure S7A). The gene discussed is ATAT1; the disease is hepatocellular carcinoma.