Notably, the promoting effects of miR-17-5p-i and miR-20a-5p-i on HCC migration were largely compromised in ERBB3-shRNA co-transfected HepG2 cells (Figure 6D left , Figure 6E upper), and greatly restored in ERBB3 rescued HCCLM3 cells when co-transfected with ERBB3 overexpression vector lacking of miR-17-5p and miR-20a-5p binding sites (Figure 6D right, Figure 6E lower). Here, ERBB3 is linked to hepatocellular carcinoma.