One recent study showed that miR-101, upregulated in DLBCL, suppressed DLBCL cell proliferation and facilitated apoptosis by inhibiting the expression of MEK1 [15], while miR-155, which is downregulated in DLBCL, suppressed DLBCL cell proliferation and facilitated apoptosis by upregulating SOCS3 expression to suppress the JAK-STAT3 signaling pathway [16]. Here, MAP2K1 is linked to diffuse large B-cell lymphoma.