DLK1 and glioblastoma: Our findings join a third category of reports suggesting that DLK1 effects are independent on Notch: DLK1-overexpressing cells were no different in their activation of Notch signaling compared with controls in a reporter assay, and DLK1 expression in no way correlated with expression of classical Notch downstream target genes in human GBM, as analyzed in TCGA data.