In the Zhongshan cohort and GSE62254, treatment with fluorouracil-based ACT was associated with better OS in patients with TNM II/III gastric cancer (Fig. 3a, b), a relationship that was identified by the CLASSIC trials.25 To evaluate the predictive value of intratumoural CD103+CD8+ T cells for ACT, we investigated the association between ACT and OS among patients with TNM II/III stage disease in the Zhongshan cohort and GSE62254 belonging to different CD103+CD8+ T cell infiltration groups. Here, ITGAE is linked to gastric cancer.