CD103+CD8+ T cells in gastric cancers exhibited a similar phenotype to those in other non-lymphoid tissues, including downregulation of lymph node homing-associated molecules (e.g. CD62L, CCR7 and TCF-1)31–33 and upregulation of tissue residency-promoting molecules (e.g. CD69, CD49a and RUNX3),34–36 which indicated the tissue-resident features of CD103+CD8+ T cells in gastric cancer. The gene discussed is CD69; the disease is gastric cancer.