PDCD1 and non-small cell lung carcinoma: To test the combination effect of PD-1 blockade and GA on antitumor activity, we evaluated cytotoxicity in an NSCLC-cell and peripheral blood mononuclear-cell (PBMC) coculture system in the presence of the anti-PD-1 monoclonal antibody (mAb) nivolumab, GA, or both.