Despite the strengthened antioxidant barrier (↑ SOD, ↑ CAT, ↑ Px/GPx, ↑ UA, ↑ TAC), in children with hypertension we observed an increase in oxidative damage to proteins (↑ AGE, AOPP) and lipids (↑ MDA), not only at the central level (plasma), but also in NWS and SWS. The gene discussed is CAT; the disease is Hypertension.