Some of these splice factor genes were common to both ALL subtypes (i.e., U2AF1 and HNRNPA1) while others were specific to BCP-ALL (i.e., HNRNPA2B1, HNRNPK and HNRNPM, SRSF5 and SRSF7) or T-ALL (SRSF3 and SRPK2). Here, U2AF1 is linked to acute lymphoblastic leukemia.