Importantly, in the adult population, carriers of a common haplotype of IL1RN involving the common allele “A” in SNP rs2234678 have a high prevalence of doctor-diagnosed asthma (odds ratio OR = 3.12, p = 0.007) [41], in line with findings in pediatric cohorts studied by Gohlke et al. [39] These reported findings suggest that the minor allele “G” and rare genotype GG at SNP rs2234678 would be protective for asthma. The gene discussed is IL1RN; the disease is asthma.