With the aim to analyze the antitumor effects induced by C. zeylanicum, the validated markers of apoptosis (caspase-3, Bax, Bcl-2), proliferation (Ki67), angiogenesis (VEGF, VEGFR-2), oxidative damage (MDA), cancer stem cells (CD24, CD44, ALDH1A1, EpCam), and cancer cell epigenetics (methylation status of five gene promoters, four parameters of histone chemical modifications, and expression of six miRNAs) were used. This evidence concerns the gene CASP3 and cancer.