The expression of liver cancer-related markers such as AFP and Arg1 were found to change significantly together with liver progenitor network genes such as Hnf1a, Hnf1b, Foxa1, Hnf4a, Foxc1, Foxc1, Foxq1 and Hes1 as well as main oncogenes and liver CSC markers implicated such as CD44, CD47, Cxcl12, Lcn2, Lyz2, CDKN1A, Mapk3, Cdh13, Cxcl14, Cxcl16, Il11 and Il33. The gene discussed is LCN2; the disease is liver cancer.