In multivariate survival analysis, higher expression of stromal PDL1 was associated with shorter LRFI for all DCIS recurrences (but not for invasive recurrences only) independent of other parameters of DCIS aggressiveness including age at diagnosis, DCIS size, nuclear grade, presence of comedo-type necrosis and margin status (HR = 2.9, 95% CI = 1.4–6.1, p = 0.005). Here, CD274 is linked to ductal breast carcinoma in situ.