Analysis of GEO profiles (GDS2416) in 33 different biopsies from 16 cervical cancer patients showed a negative correlation between the expression of UBE2L3 and CBX3 (a gene encoding HP1γ), whereas the expression of UBE2L3 and CBX1 (a gene encoding HP1β) showed a positive correlation (Fig. 4b). The gene discussed is CBX3; the disease is cervical cancer.