To further examine the EphA2 expression levels among other HCC cell lines, we collected three other HCC cell lines, PLC-5, Sk-Hep-1 and Hep3B, and determined the expression level of EphA2 and S897 phosphorylation status by western blotting (Supplementary Fig. 1a). The gene discussed is EPHA2; the disease is hepatocellular carcinoma.