GCNT1 and infection: Chimeric mice were then infected with a low dose of Mtb. Mice in the Gcnt1−/−→Gcnt1−/− group presented a different survival curve compared to all other groups, where one animal (representing 14.3%) succumbed to infection after 24 days (Fig. 4c), and also higher lung bacterial burdens 30 days post-infection than any other group (Fig. 4d), paralleling the increased susceptibility to infection of Gcnt1−/− mice.