Histopathological analysis of the infected chimeric animals showed that although Gcnt1−/−→C57BL/6 mice presented edema and larger necrotic areas when compared to the C57BL/6→C57BL/6 group, Gcnt1−/−→Gcnt1−/− animals presented the most exuberant pathology with severe inflammation, edema, vast necrosis and bronchopneumonia (Fig. 4e and Fig. S4B). Here, GCNT1 is linked to bronchopneumonia.