GCNT1 and infection: When comparing all experimental groups, we observed that both the Gcnt1−/−→C57BL/6 and the Gcnt1−/−→Gcnt1−/− chimeric animals presented significantly higher neutrophils in circulation upon reconstitution and before infection (Fig. 4b), suggesting that hematopoietic deficiency of Gcnt1 is sufficient to promote neutrophilia.