GCNT1 and tuberculosis: Neutrophils are widely described as detrimental in TB,1–4 and an interferon-inducible neutrophil-driven blood transcriptional signature was defined in human TB.25 Interestingly, human neutrophils are decorated with sialylated antigens, most notably sLex, which biosynthetic pathway involves Gcnt1 enzymatic activity.7 We found alterations in the expression of several glycosyltransferases in whole blood of active TB patients as compared to controls.