The histopathological features observed during infection with low doses of Mtb were recapitulated and exacerbated for those with high doses, with infected Gcnt1-/- mice presenting extensive lung pathology, particularly extensive necrosis, and histological features of bronchopneumonia (Table 1, Fig. 1i, g and Fig. S1E). Here, GCNT1 is linked to bronchopneumonia.