Moreover, after miR-497 overexpression or FGFR1 knockdown, the migration ability of AGAP2-AS1-overexpressing CRC cells was reversed (Figure 6D), indicating that AGAP2-AS1 played a carcinogenic role by sponging miR-497 and upregulation of FGFR1 expression in CRC. This evidence concerns the gene FGFR1 and colorectal carcinoma.