There was a strong correlation between tumour static SUV values and Ki values (Patlak R2 = 0.95; 2TC R2 = 0.87, n = 9, Fig. 5), indicating that the static SUV images provided a close representation to HER2-specific binding since parametric Ki images reflect the specific uptake solely and eliminate any non-specific binding that increases background uptake. The gene discussed is ERBB2; the disease is neoplasm.