While pituitary tumors and pheochromocytoma are rarely seen in MEN1 syndrome, the constellation of paraganglioma, pheochromocytoma, and pituitary tumor (“3P” association) is now increasingly recognized in patients with SDHx mutations (111, 112) with a characteristic histological phenotype (111) and pituitary adenomas developing in a Sdhb-knockout mouse model (113). Here, SDHB is linked to pheochromocytoma.