The same microRNAs may even play different roles in different tumor subtypes: miR-410-3p significantly upregulates proliferation, invasiveness, cyclin B1 levels and activation of MAPK, PTEN/AKT, and STAT3 signaling pathways in gonadotroph and corticotroph cells but not in somatotroph cells (267). This evidence concerns the gene AKT1 and neoplasm.