The fGGN-based HCC stratification study [56] showed that the differentially upregulated genes in iHCC3 also included the mammalian target of rapamycin (mTOR), the oncogene Myc, genes involved in the G-to-M–phase progression of the cell cycle and genes involved in the epithelium-to-mesenchymal transition. This evidence concerns the gene MTOR and hepatocellular carcinoma.