GPT and metabolic dysfunction-associated steatohepatitis: However, clinical trials involving vitamin E administration have only shown modest improvement in liver biochemistries so far: results include modestly reduced alanine transaminase (ALT) levels in children with NAFLD [26], reduced ALT and aspartate transaminase (AST) levels in NASH [27], and reduced ALT, AST and γ-glutamyl transpeptidase (GGT) when combined with ursodeoxycholic acid (UDCA) [28].