With this information as a background, the aim of this study is to test the hypothesis that antidepressant compounds with low Ki values—that is strong receptor binding affinities—for the serotonin 5-HT2C receptor, histamine (H1) receptors, or norepinephrine transporter (NET) will be associated with the highest odds of somnolence. This evidence concerns the gene SLC6A2 and Coma.