CXCL8 and neoplasm: The expression of CXCL8 in urine specimens and the tumour microenvironment of bladder cancer patients is significantly higher than that of healthy volunteers (Pignot et al., 2009; Sheryka et al., 2003), and the overexpression of CXCL8 is positively correlated with significantly reduced survival of patients overall (Zhang et al., 2014).