Compared with AC-TH regimen, patients recommending to PH regimen were more often with older age (odds ratio [OR] 0.002, 95% confidence interval [CI] 0.000-0.017, P<0.001), small tumor size (OR 88.841, 95% CI 12.364-638.387, P<0.001), negative ALN (OR 0.007, 95% CI 0.001-0.084, P<0.001), low Ki-67 (OR 4.620, 95% CI 1.269-16.821, P=0.020), and with comorbidities (OR 2.960, 95% CI 0.865-10.129, P=0.084). The gene discussed is MKI67; the disease is neoplasm.