miR-19a-3p was identified as a key oncogenic miRNA of the miR-17-92 cluster 8; it is dysregulated in many types of cancer, including gliomas, bladder cancer, breast cancer, and pancreatic, gastric, and laryngeal squamous cell carcinoma, whereas PPAR-α, PTEN, and RUNX3 have been identified as its target genes. The gene discussed is PPARA; the disease is central nervous system cancer.