FRAT1 and central nervous system cancer: Real-time PCR confirmed relative mRNA expression of FRAT1 and β-catenin in the glioma tissues of mice-FRAT1-KD were significantly lower than mice-vector respectively (p<0.001 for FRAT1, p<0.01 for β-catenin); but there was no significant difference in relative mRNA expression of FRAT1 and β-catenin in glioma tissues between mice-vector and mice-control (Fig. 2C and D).