CRP and psychiatric disorder: For instance, recent studies have shown that early life adversities, such as parental mental illness (O’Connor et al., 2019) and the number of adversities experienced prior to age 9 (Flouri et al., 2020, Slopen et al., 2013) were associated with elevated Interleukin-6 (IL-6) and C-Reactive Protein (CRP) levels in childhood and adolescence.