SOX2-OT and pancreatic ductal adenocarcinoma: SOX2OT has attracted growing attention due to its important role on the tumorigenesis of breast,11 gastric,12 ovary,13 lung,14 pancreatic ductal adenocarcinoma,15 colorectal cancer16 and so on,17, 18 suggesting that SOX2OT could serve as diagnosis marker and therapy target for various cancers.