Similarly, some targets of miR-299-3p were reported such as ABCE1 in lung cancer16, OCT4 in breast cancer and fibrosarcoma17, SHOC2 in thyroid cancer18, and AR in prostate cancer19 suggesting that restoring miR-299-3p expression in prostate cancer may have pleiotropic effects mediated by several target genes. Here, AR is linked to Familial prostate cancer.