AFP and hepatocellular carcinoma: However, these findings contrasts with those of Özkan H et al. 24, who found that GP73 has specificity and sensitivity lower than AFP as well as with Qiao Y. et al., 2014 and Liu T.25,26, who reported that GP73 is not a suitable marker for the detection of HCC because its elevation is not only related to HCC patients but also to cirrhotic patients.