TNC is highly expressed in many chronic lung diseases like chronic obstructive pulmonary disease (COPD), bronchopulmonary dysplasia (BPD), idiopathic pulmonary fibrosis (IPF), respiratory distress syndrome (RDS) and asthma, where it is even considered as a marker of severity12–16. The gene discussed is TNC; the disease is bronchopulmonary dysplasia.