HNF4A and neuroblastoma: In order to explore the significance of HNF4A and RUNX1 in NB, Kaplan–Meier curves of 498 patients (GSE49710) showed that high HNF4A and RUNX1 levels were correlated with favorable overall survival in NB patients (p = 0.053 and 0.019, respectively, Fig. 1b).