PDK1 and cancer: Moreover, coupled with the consistent high mRNA intensity and protein expression levels of PDK1 in earlier data, from IHC-based proteome analyses using the human protein atlas platform version 18.1 (https://www.proteinatlas.org/ENSG00000152256-PDK1/pathology/tissue/liver+cancer#img) we observed a significant positive correlation between PDK1 immunoreactivity/expression and disease stage/progression (Figure 1D).