Interestingly, as shown in Figure 7A,C, we found that in tumor-rejecting C51 FL Rnaset2-injected mice there was a gain of F4/80+ mature macrophages as well as a two-fold increase of percentage of CD4+ T helper cells, whereas CD8+ T cells were not modulated in the different groups investigated. This evidence concerns the gene RNASET2 and neoplasm.