Importantly, there was also a statistically significant retardation of C51 tumor growth in C51 FL Rnaset2-injected mice in comparison to both empty vector C51 E and C51 P control mice (Figure 3B), and a significant rate of tumor-free survival mouse (33%, i.e., 2 out of 6 mice) (Figure 3C) that was confirmed with similar results in another set of five injected mice per group (40% of tumor-free survival mouse, i.e., 2 out of 5 mice). Here, RNASET2 is linked to neoplasm.