Next, C51 mouse colon carcinoma cells overexpressing the murine Rnaset2 gene (C51 FL Rnaset2) were inoculated in parallel with parental, untransfected C51 P and empty vector (C51 E) cancer cells in distinct groups of BALB/c mice in order to investigate after two months its in vivo capacity to resist a homologous re-challenge with C51 P cells and the features of infiltrating immune cells. Here, RNASET2 is linked to colon carcinoma.