RNASET2 and neoplasm: Compared to control mice, M1 macrophages were massively recruited in the Rnaset2-expressing tumors at 2 weeks post-tumor inoculation, with a concomitant inhibition of both M2 macrophages and MDSCs influx, whereas at 3 weeks post-injection a statistically significant expansion of intra-tumor CD8+ T cells population in mice injected with Rnaset2-overexpressing C51 cells was observed.