CYP24A1 and Familial prostate cancer: When investigating the interaction, simultaneously with the SNPs among CYP17, CYP19, CYP24A1, and CYP1B1 (rs10012, rs17115144, rs1048691, rs11636639, and rs3751592), this polymorphism showed a slight interaction in increasing the risk of prostate cancer development (permutation p = 0.04, CVC (cross-validation consistency), 10/10; testing accuracy, 0.60) in African Americans [82].