However, Kristin G.I. Mohn et al. [8] stimulated PBMC during acute and convalescent patients, suggesting that significantly lower frequencies of influenza-specific CD8+ compared with CD4+ IFN-γ T-cells in acute patients, while high levels of both CD4+ and CD8+ T cells directed against conserved core antigens in convalescent patients. The gene discussed is CD4; the disease is influenza.