We also found hepatic mRNA expression of M2 markers (IL-10, CD163, and Ym-1) in NASH mice were induced as compared to that in NCD-fed control mice (Figure 5); however, myricetin-treated to NASH mice further increased hepatic mRNA expression of CD163 and IL-10 markers when compared with vehicle-treated to those animals, but there was no difference in Ym-1 gene expression (Figure 5). The gene discussed is IL10; the disease is metabolic dysfunction-associated steatohepatitis.