In cancer, Pin1 expression and activity are aberrantly elevated in many malignancies, which are regulated in genetic, transcriptional, post-transcriptional, and PTMs levels (Bao et al., 2004; Takahashi et al., 2008; Lee et al., 2011b, 2014; Li et al., 2013; Lu and Hunter, 2014; Luo et al., 2014; Zhou and Lu, 2016). Here, PIN1 is linked to cancer.