DAPK1 and Alzheimer disease: DAPK1 is a calcium/calmodulin-dependent Ser/Thr kinase that is involved in cell death, and its deregulation is implicated in cancer and AD (Cohen et al., 1997; Inbal et al., 1997; Kissil et al., 1997; Kim et al., 2014, 2016, 2019; Zhao et al., 2015; You et al., 2017; Chen et al., 2019).