Knockdown of LAMC2 decreased the invasive activity of TMK-1 and MKN-1 cells (the two cell lines in the study where WNT5A abundance best correlated with that of LAMC2), whereas Wnt5a showed a tendency to correlate with laminin γ2 expression in scirrhous GC biopsies (Yamamoto et al., 2009). The gene discussed is WNT5A; the disease is gastric cancer.