Furthermore, a chi-square test showed that compared with GPSM2-cytoplasm group, GPSM2-nucleus group was significantly correlated with HER2 receptor-positive (p = 0.010), Ki67-positive (p = 0.001), increased T stage (p = 0.001), lymph node metastasis (p = 0.015), and higher TNM stage (p = 0.029) (Table 2). The gene discussed is MKI67; the disease is metastatic malignant neoplasm in the lymph nodes.