Experimental circadian disruption relevant to environmental cues like light-light cycle (LL) is considered for glioma tumor growth by promoting an anabolic metabolism processes where results indicated that key enzymes involved in lipogenesis (acetyl-coenzyme A carboxylase, fatty acid synthase, and PPAR-γ), and glucose uptake (Glucose transporter 1), were upregulated in the tumor microenvironment obtained from sLL in-vivo model. The gene discussed is PPARG; the disease is central nervous system cancer.