This statement could be supported by previous studies showing that S15 phosphorylation of TP53 contributed mutant TP53 stability, thereby prolonging cell viability in ovarian cancer cells (76), and S392 phosphorylation in mutant TP53 could lead to tumor progression in esophageal squamous cell carcinoma (77). The gene discussed is TP53; the disease is esophageal squamous cell carcinoma.