This demonstrates that mitochondrial function is impaired in BRCA1 mutant tumors, while enriched genes correspond to mitochondrial organization (Figure 7N), and BRCA1 mutant tumor accumulates more M2‐polarized macrophages, as well as containing less activated CD8+ T cells than the TP53 mutant tumors (Figure 7O,P). This evidence concerns the gene TP53 and neoplasm.