TRIM32 is significant for the STING‐TBK1 interface following Sendai virus (SeV) or HSV1 infectivity.11 Ubiquitin ligase RNF5‐mediated K48‐linked ubiquitination negatively regulates STING and degrades upon viral infection.65 RNF26 is recognized as an E3 ligase for K11‐linked polyubiquitination of STING at the equivalent Lys150 STING residue. This evidence concerns the gene STING1 and viral infectious disease.