Reduced expression of ICAM-1 could play a role in the suppression of tumor progression in many cancer cells, such as breast cancer (Ogawa et al., 1998), gastric cancer (Fujihara et al., 1999), lung cancer (Kotteas et al., 2014) and colorectal cancer (Maeda et al., 2002). This evidence concerns the gene ICAM1 and breast cancer.