Amperometric detection at screen-printed carbon electrodes (SPCEs) was performed to evaluate the diagnostic potential of a novel autoantibody panel composed of eight TAAs (GTF2B, MAPKAPK3, PIM1, PKN1, SRC, STK4, SULF1, and p53) previously validated or not validated for CRC diagnosis because of their difficulty to be expressed or purified 7, 9. The gene discussed is PKN1; the disease is colorectal carcinoma.