CNTNAP4 and Parkinson disease: However, CNTNAP4 concentration was increased in male PD patients as compared with male controls (male controls: 97.01 ± 13.17 pg/mL and male PD patients: 196.20 ± 30.70 pg/mL; P = 0.0072; Figure 11G), and female PD patients (PD patients: female: 114.30 ± 19.08 pg/mL and male: 196.20 ± 30.70 pg/mL; P = 0.0127; Figure 11G).