CD274 and osteosarcoma: The IHC images and the corresponding IHC score of FGD1 and PD-L1 are presented in Figure 5F and Figure 5H. Furthermore, FGD1 was found to be positively correlated with PD-L1 in the osteosarcoma tissue microarray (P < 0.001, Spearman correlation r = 0.5182) (Figure 5G).