Moreover, GLI1+/IFT20+ mRNA expression also correlated with shorter OS (median survival of cohort B, 101 months versus superior to 150 months (p=0.09) and median survival of TCGA, 62.84 months versus greater than 150 months (p<0.0001)) compared to the no primary cilium signature (Figure S7A and Figure 5C), strongly demonstrating that tumors expressing more primary cilia and without VDAC1-ΔC were more aggressive in a ciliopathy model; thus confirming our in vitro findings. The gene discussed is VDAC1; the disease is ciliopathy.