It is therefore possible to envisage specific treatment for these groups: Temsirolimus 60 or Everolimus, specific inhibitors of mTOR 61 that block proliferation, in combination with small molecule inhibitors that prevent EMT such as EW-7197 or IN-1130, through a block in TGFβ 1 and 2, have already been used in metastatic breast and lung cancer 62. The gene discussed is MTOR; the disease is lung cancer.