The results shown that expression of RIPK4 (HR=0.58, log-rank P = 0.00042) was correlated with worse OS for ccRCC patients, as well as CDC42(HR=0.6, log-rank P=0.001), PTPN11 (HR=0.6, log-rank P=0.0011), KITLG (HR=0.55, log-rank P=0.00012), IGF1R (HR=0.4, log-rank P = 2.3e-08), FLT1 (HR=0.51, log-rank P=1.9e-05), AURKB (HR=2.1, log-rank P=2.8e-06), GNA13 (HR=0.63, log-rank P=0.0027), DLG2 (HR=0.63, log-rank P=0.0033) (Figure 3a-i). This evidence concerns the gene IGF1R and nonpapillary renal cell carcinoma.