MRPL3 and lung cancer: To further determine the expression of these hub genes in LUSC, we used immunohistochemistry results from the Human Protein Atlas database to show that MRPL15, MRPL13, MRPL4, MRPL3, MRPL24, MRPS12, MRPL11, MRPL21, MRPL36, and MRPL47 were significantly increased in lung cancer compared with normal lung tissue (Figure 3).