Besides POF1B, four autosomal differential expressed genes related to the term “premature ovarian failure” (HP:0008209) in the Human Phenotype Ontology (HPO) database were found and could have influenced in the only apparent phenotype of the patient: CEP290 (log2 fold change value = 1,75; q value = 0,004), HFM1 (log2 fold change value = -7,34; q value = 0,001), STAG3 (log2 fold change value = -5,26; q value = 0,00001), and NPHP4 (log2 fold change value = -8,65; q value = 0,0000003). The gene discussed is POF1B; the disease is primary ovarian failure.